Total synthesis of (±)-maistemonine and (±)-stemonamide.
نویسندگان
چکیده
The first total synthesis of polycyclic Stemona alkaloid maistemonine has been achieved. The efficient approach features a stereoselective intramolecular Schmidt reaction, a ketone-ester condensation, and a Reformatsky reaction. Additionally, another Stemona alkaloid stemonamide was divergently synthesized from a common intermediate.
منابع مشابه
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This review deals with the synthesis of alkaloids using radical cyclizations. Emphasis has been placed on radical cascades that provide synthesis of (-)-cephalotaxine, (±)-stemonamide, and (±)-isostemonamide.
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ورودعنوان ژورنال:
- Chemical communications
دوره 47 6 شماره
صفحات -
تاریخ انتشار 2011